Ro5-4864, also referred to as 4′-Chlorodiazepam, is a potent ligand for the translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR). Unlike traditional benzodiazepines that act on central GABA-A receptors, Ro5-4864 is non-sedative and is specifically used to study mitochondrial activity, neuroinflammation, and steroidogenesis.
This compound has shown strong binding affinity to the outer mitochondrial membrane and plays a critical role in the regulation of mitochondrial functions, including apoptosis and neurosteroid synthesis. It is widely used in neuroscience and cancer biology research.
Dopechem.com offers 4′-Chlorodiazepam in its purest form for professional-grade research, helping labs conduct reliable and reproducible experiments.
⚠️ Note: This compound is strictly not for therapeutic or diagnostic use in humans or animals.
🔬 Common Research Applications Ro5-4864
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TSPO receptor binding studies
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Mitochondrial function and apoptosis research
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Neuroinflammation and CNS modulation
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Investigation of neurosteroid biosynthesis
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Behavioral neuroscience studies
⚠️ Potential Side Effects (In Case of Misuse)
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Mitochondrial disruption
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Hormonal imbalance
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Mild agitation or restlessness in animal models
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Altered behavior or neurosteroid production
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Risk of cytotoxicity at high doses
Nembutal Pentobarbital Sodium 50mg/ml – High-Grade Laboratory Solution 

